CAOPORN成人免费公开,欧美FREESEX黑人又粗又大 ,欧美狠狠入鲁的视频777色,主仆调教SM束缚绳索捆绑

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
中文字幕日韩精品无码内射,亚洲精品乱码久久久久久自慰,波多野结衣绝顶大高潮
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-CD62p  antibody (bs-0561R)
訂購熱線:400-901-9800
訂購郵箱:sales@www.tjshangbang.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@www.tjshangbang.com
說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)

產(chǎn)品編號 bs-0561R
英文名稱 Rabbit Anti-CD62p  antibody
中文名稱 P選擇素/白細(xì)胞內(nèi)皮細(xì)胞粘附分子3抗體
別    名 P-selectin; CD_antigen: CD62P; CD62 antigen-like family member P; GMP 140; GMP-140; GMRP; Granule membrane protein 140; Granulocyte membrane protein; GRMP; LECAM 3; LECAM3; Leukocyte endothelial cell adhesion molecule 3; Leukocyte-endothelial cell adhesion molecule 3; P Selectin; PADGEM; Platelet activation dependent granule-external membrane protein; PSEL; sp-selectin; LYAM3_HUMAN.  
Specific References  (7)     |     bs-0561R has been referenced in 7 publications.
[IF=25.809] Liu G et al. Engineering Biomimetic Platesomes for pH‐Responsive Drug Delivery and Enhanced Antitumor Activity. Adv Mater. 2019 Jun 20:e1900795.  WB ;  Mouse.  
[IF=16.744] Haifeng Gong. et al. Platelet shipped IL-10 enhances drug delivery for attenuating I/R- or UUO-induced renal injury. CHEM ENG J. 2023 Apr;462:142258  WB ;  Rat.  
[IF=9.473] Stanley M. H. Chan. et al. Inhibition of oxidative stress by apocynin attenuated chronic obstructive pulmonary disease progression and vascular injury by cigarette smoke exposure. BRIT J PHARMACOL. 2023 Mar;:  IHC ;  Mouse.  
[IF=6.419] Qi-Rui Li. et al. Platelets are highly efficient and efficacious carriers for tumor-targeted nano-drug delivery. Drug Deliv. 2022;29(1):937-949  IHC ;  Mouse.  
[IF=5.21] Ma, Yanqin, et al. "Inflammatory responses induced by fluoride and arsenic at toxic concentration in rabbit aorta." Archives of toxicology 86.6 (2012): 849-856.  WB ;  Rabbit.  
[IF=1.38] Hu, Zhibin, et al. "Comparative analysis of preservation method and intermittent perfusion volume on the expression of endothelial and inflammatory markers by coronal artery and myocardium in porcine donor hearts." ASAIO journal (American Society for Artificial Internal Organs: 1992) (2014).  IHC-P ;  Pig.  
[IF=0] Rui-Kai and Jian Effects of xinfeng capsules on expression of platelet granule membrane protein 140 and platelet cluster of differentiation 40 ligand in peripheral blood of adjuvant arthritis rats. (2012) Int.J.Rheumato. 2012:139696  FC/FACS ;  Rat.  
研究領(lǐng)域 心血管  細(xì)胞生物  免疫學(xué)  干細(xì)胞  細(xì)胞粘附分子  上皮細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Rat,Pig (predicted: Mouse,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,Flow-Cyt=1μg/Test,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 88kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse P-selectin: 701-768/768 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]

Function:
Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.

Subunit:
Interacts with SNX17. Interacts with PSGL1/SEPL and PODXL2 and mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of PSGL1 and PODXL2, and specific tyrosine sulfation on PSGL1.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.

DISEASE:
Defects in SELP may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.

Similarity:
Belongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 9 Sushi (CCP/SCR) domains.

SWISS:
Q01102

Gene ID:
6403

Database links:

Entrez Gene: 6403 Human

Entrez Gene: 20344 Mouse

Entrez Gene: 25651 Rat

Omim: 173610 Human

SwissProt: P16109 Human

SwissProt: Q01102 Mouse

SwissProt: P98106 Rat

Unigene: 73800 Human



P-選擇素(P—selectin)是細(xì)胞黏附分子選擇素家族的主要成員,又稱CD62p,可以介導(dǎo)各種白細(xì)胞和腫瘤細(xì)胞的粘附。
CD62p又稱GMP—140或PADGEM蛋白(血小板活化依賴α顆粒膜蛋白),它在血小板與單核細(xì)胞及中性粒細(xì)胞相互作用中起關(guān)鍵作用。
產(chǎn)品圖片
Sample: K562(Human) Cell Lysate at 30 ug Huvec(Human) Cell Lysate at 30 ug Jurkat(Human) Cell Lysate at 30 ug Primary: Anti-CD62p (bs-0561R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 140'90 kD Observed band size: 130 kD
Tissue/cell: rat colon tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-P-selectin Polyclonal Antibody, Unconjugated(bs-0561R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: rat pancreas tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-P-selectin Polyclonal Antibody, Unconjugated(bs-0561R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Blank control: HUVEC cells(blue). Primary Antibody:Rabbit Anti-CD62p antibody(bs-0561R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA. Protocol The cells were fixed with 2% paraformaldehyde (10 min) .Primary antibody (bs-0561R, 1μg /1x10^6 cells) were incubated for 30 min on the ice, followed by 1 X PBS containing 0.5% BSA + 1 0% goat serum (15 min) to block non-specific protein-protein interactions. Then the Goat Anti-rabbit IgG/PE antibody was added into the blocking buffer mentioned above to react with the primary antibody at 1/200 dilution for 30 min on ice. Acquisition of 20,000 events was performed.
版權(quán)所有 2004-2026 www.www.tjshangbang.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
黄片久久久久久久久久久| 亚洲欧美一区二区三区麻豆| 蜜桃AV噜噜一区二区三区| 国产精品自在自线视频| A级毛片无码久久精品免费| 丰满少妇被猛烈进入高清APP| 可以看伦理片的网站| 吃奶呻吟打开双腿做受动态图| 多毛熟女HDVIDOS| 无码任你躁久久久久久老妇| 欧美久久天天综合香蕉伊| www.一区二区三区| 久久亚洲AV成人网站玖玖| 无遮挡国产高潮视频免费观看| 国产精品福利一区二区| 亚洲最大成人网 色香蕉| 我和子发生了性关系视频| 翁公在厨房把她腿分得更开| 九九精品免视频国产成人| 国产婷婷色综合AV蜜臀AV| 女体天国浴场盗摄在线观看| 精品欧美一区二区vr在线观看| 欧美日韩一区视频| 99精品国产久热在线观看蜜桃| 久久97久久97精品免视看| 蜗牛影视在线观看免费完整版| 欧美激情在线精品三区| 看大片人与拘牲交| 亚洲国产成人极品综合| 日本韩国欧美一级片网站| 国内精品线在线观看| 免费特级毛片| 深夜福利视频在线播放| 成 人 免费 黄 色 网站无毒下载| 少妇白洁小说在线阅读| 国产成人午夜高潮毛片| 国产在线精品无码不卡手机免费| 久久精品国产亚洲7777| 天美传媒果冻传媒国产日本| 久久国产精品无码网站| 2021最新在线精品国产|