| 產(chǎn)品編號(hào) | bsm-2069M |
| 英文名稱 | Ketamine(4E2) Mouse mAb |
| 中文名稱 | 氯胺酮單克隆抗體 |
| 別 名 | (±)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride. |
| 產(chǎn)品類(lèi)型 | 小分子抗體 |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 藥物及化合物 |
| 抗體來(lái)源 | Mouse |
| 克隆類(lèi)型 | Monoclonal |
| 克 隆 號(hào) | 4E2 |
| 交叉反應(yīng) | (predicted: Ketamine) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 0.27419 kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Ketamine |
| 亞 型 | IgG1 |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Ketamine is a drug used in human and veterinary medicine. Its hydrochloride salt is sold as Ketanest, Ketaset, and Ketalar. Pharmacologically, ketamine is classified as an NMDA receptor antagonist.[2] At high, fully anesthetic level doses, ketamine has also been found to bind to opioid Mu receptors and sigma receptors.[3][4] Like other drugs of this class such as tiletamine and phencyclidine (PCP), it induces a state referred to as "dissociative anesthesia"[5] and is used as a recreational drug. 氯胺酮（Ketamine），又稱為開(kāi)他敏、K粉，是一種非巴比妥類(lèi)靜脈全麻藥。氯胺酮（ketanine）是苯環(huán)己哌啶（phencyclidine）的衍生物。臨床所用的氯胺酮是右旋氯胺酮和左旋氯胺酮兩對(duì)映異構(gòu)體的消旋體。實(shí)驗(yàn)研究表明，右旋氯胺酮的麻醉效價(jià)為左旋氯胺酮的4倍，而蘇醒期精神運(yùn)動(dòng)反應(yīng)卻較少。市售氯胺酮為其鹽酸鹽，易溶于水，pH3.5～5.5，pK a 7.5。 由于氯胺酮具有一定的精神依賴性，易使人形成癮癖，便成為娛樂(lè)場(chǎng)所的常用毒品。這種外觀純白的細(xì)結(jié)晶體為鼻吸或溶于飲料后飲用，能興奮心血管，吸食過(guò)量可致死。吸食者在其作用下會(huì)瘋狂搖頭，可能造成心力、呼吸衰竭。吸食過(guò)量或長(zhǎng)期吸食，心、肺、神經(jīng)都可能造成致命損傷。 充分認(rèn)識(shí)“K粉”濫用對(duì)人體和社會(huì)造成的危害。不要輕信“K粉”不會(huì)成癮的說(shuō)法而去嘗試，目前我國(guó)已將“K粉”列入和冰毒、嗎啡、度冷丁等同屬于毒品類(lèi)，并嚴(yán)厲打擊販賣(mài)及吸食“K粉”。 |
