| 產(chǎn)品編號(hào) | bs-46017P |
| 英文名稱 | Recombinant SARS-Cov-2 Spike S1 protein (N501Y, K417N, E484K), His (HEK293) |
| 中文名稱 | 重組SARS冠狀病毒2 Spike突變蛋白S1(N501Y, K417N, E484K) His tag |
| 別 名 | SARS-CoV-2 spike protein; 2019-nCOV Spike protein; Spike glycoprotein; Spike protein ; Surface glycoprotein; SPIKE_SARS2; 2019-nCOV Spike protein S1(N501Y, K417N, E484K), Recombinant (His Tag); Recombinant SARS-COV-2 Spike S1 (N501Y, K417N, E484K) . ;Recombinant SARS-Cov-2 Spike S1 protein (N501Y, K417N, E484K), His (HEK293) 突變型新冠蛋白; 新冠病毒S蛋白突變體（N501Y, K417N, E484K）; 重組新冠病毒 Spike突變蛋白S(N501Y, K417N, E484K); 新型冠狀病毒Spike突變體蛋白; |
| 理論分子量 | 73kDa |
| 檢測(cè)分子量 | 120-140 kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | ＞0.5 mg/ml |
| 物 種 | SARS-Cov-2 |
| 序 列 | 16-685/1273 |
| 純 度 | >95% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內(nèi)毒素 | Not analyzed |
| 表達(dá)系統(tǒng) | HEK293 cell |
| 活性 | Yes |
| 標(biāo)簽 | His |
| 緩 沖 液 | Lyophilized from 0.22 um filtered solution in 2X PBS (pH=7.4). Normally 5% trehalose is added as protectant before lyophilization. |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
SARS-CoV-2 exploits angiotensin-converting enzyme 2 (ACE2) as a receptor to invade cells. It has been reported that the UK and South African strains may have higher transmission capabilities, eventually in part due to amino acid substitutions on the SARS-CoV-2 Spike protein.The results of a study show the N501Y replacement in this region of the interface (present in both the UK and South African strains) should be favorable for the interaction with ACE2, while the K417N and E484K substitutions (South African strain) would seem neutral or even unfavorable. SWISS: P0DTC2 Gene ID: 43740568 |
