| 產(chǎn)品編號(hào) | V1904-AP |
| 英文名稱 | Human CEA Mouse mAb, AP conjugated |
| 中文名稱 | AP標(biāo)記的癌胚抗原單克隆抗體 |
| 克 隆 號(hào) | 6C9 |
| 理論分子量 | kDa |
| 檢測(cè)分子量 | |
| 緩 沖 液 | 0.01M PBS (pH7.4). |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. SWISS: P40199 Gene ID: 4680 應(yīng)用推薦（Capture-Detection）: V1906-V1907 |
